Welcome to Technology Trends

Label-Free Detection is used for Binding Interaction Analysis. Bio-Layer Interferometry and Surface Plasmon Resonance are used for label-free biosensor binding assay methods. Biosensor Assays vs. ELISA are compared. Calorimetry and Microscale Thermophoresis are used for determining the optimal biosensor platform. Key Octet ® BLI System Attributes are highlighted. Typical Assay Workflow is discussed. Analysis on FC-Gamma Receptor Interactions in Octet ® Platforms is discussed. Selecting an assay format is discussed. Quantitation on Octet ® BLI Platforms is also discussed.

Quantification Assay for Antiviral Virus (AV) Concentration Monitoring

• Biomolecules' interactions are key triggers for biological processes, providing targets for drug discoveries.
• Techniques used to characterize these interactions need to mirror the level of biological complexity.
• Label-free biosensor binding assay methods include biosensor-based Bio-Layer Interferometry (BLI), sensor chip-based Surface Plasmon Resonance (SPR), solution-based Isothermal Titration Calorimetry (ITC), and Microscale Thermophoresis (MST).
• BLI and SPR monitor binding interactions based on molecular accumulation during complex formation.
• BLI platforms measure light interference originating from the tip of the biosensor surface, where light wavelengths are made to reflect from two layers: a biocompatible layer at the end of the biosensor surface and an internal reference layer.
• The interference pattern (i.e., spectral shift) in real time provides kinetics data on molecular interactions.

I will receive information, tips, and offers about Office and other Technology Trends products and services. Privacy Statement.

White Paper from Technology Trends